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In a study by Rosato and coworkers who evaluated the NAC effects on vascular system function in Systemic Sclerosis patients, authors concluded that NAC improved vascular renal function in patients with low severity of disease (NAC dosage: 15 mg/kg/hour for 5 hours)[62]

doi: 10.1038/s41401-021-00801-6 27 GeXJiangFWangMChenMLiYPhippsJet al

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Paracetamol overdose during pregnancy NPIS advises that for pregnant patients, the toxic dose should be calculated using the patients pre-pregnancy weight, and the acetylcysteine dose should be calculated using the patients actual pregnant weight