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Paradoxically, elevated ROS levels and cardiac dysfunction were also observed in DN-NOX4 mice under IR challenge, indicating that high NADPH and GSH levels also enhance ROS generation and induce reductive stress by mechanisms yet to be determined (116)

GLOBAL GLUTATHIONE MARKET SIZE, BY GELS, BY GROUP, 2018-2032 (USD MILLION) TABLE 113

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The relative importance of T cell subsets in immunity and immunopathology of airborne Mycobacterium tuberculosis infection in mice