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As anticipated, Rest RTKO mice exhibited obvious attenuation of renal fibrosis, as evaluated by hematoxylin and eosin (H&E) staining, Massons staining, and immunohistochemical staining of -SMA and fibronectin (Figure 8A), along with reduced Scr and BUN levels (Figure 8, B and C)

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Tang Q, Chen H, Mai Z, Sun H, Xu L, Wu G, et al