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Description
Smoking-related catecholamine stimulation is associated with increased heart rate (HR), blood pressure (BP), and coronary vasoconstriction, which are risk factors for CVD 3

The person who starts smoking by age 19 typically takes about 20 years to finally quit

South Dakota raised the smoking age to 21 in 2021 to align with federal law

Key Takeaways Nicotine leaves the body quickly, but its metabolite lasts much longer: Nicotine itself is usually eliminated within 13 days, but cotinine (the primary metabolite tested for) can remain detectable for up to 10 days in blood and up to 3 weeks or longer in urine for heavy users
