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Description
According to the Center for Disease Control in 2018, fewer than one in ten adult cigarette smokers succeed in quitting each year, while over half of them attempted to in the previous year
Furthermore, the FDA has slowed down fast-track approvals for nicotine pouches, citing concerns over youth usage

Notably, while simultaneous substitution of these residues negatively impacts ternary complex formation and ubiquitylation of BRD4 BD1 (Extended Data Fig

95% CI = 0.10, 0.06
