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Most current assessments of the epidemiological and toxicological data suggest, however, that low-yield products are associated with far less health benefit than predicted based on FTC assay-generated tar, CO, and nicotine levels

You'll feel a tingling sensation for a moment, which is how you know the nicotine is being released

Kaufmann, S

you may feel a warm or tingling sensation occasionally move the lozenge from one side of your mouth to the other until completely dissolved do not eat or drink 15 minutes before using or while the lozenge is in your mouth to improve your chances of quitting, use at least 9 lozenges per day for the first 6 weeks do not use more than one lozenge at a time or continuously use one lozenge after another since this may cause you hiccups, heartburn, nausea or other side effects do not use more than 5 lozenges in 6 hours