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Flare-ups can be triggered by: Injury or infection in the mouth Some medications Allergic reactions Stress Dental problems Oral lichen planus is more common among people who take certain medications, such as antifungals or non-steroidal anti-inflammatory drugs (NSAIDs)

Clinicians use this parameter to describe the intensity of tobacco smoking throughout the patient's life

In addition, previous studies have reported that nicotine augments anti-apoptotic signaling and chemotactic migration of neutrophils, leading to their accumulation and promotion of local tissue damage 95,96

This systematic review and meta-analysis of studies conducted in both high-income (HICs) and low- and middle-income countries (LMICs) synthesised existing evidence on associated factors of smoking and cessation behaviour among PLWH