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J Immunol 175:2684-2691 [DOI] [PubMed] [Google Scholar] Vassallo R, Kroening PR, Parambil J, Kita H

This method can theoretically be accomplished through repeated changes to cigarettes with lower nicotine levels, by gradually reducing the number of cigarettes smoked daily, or by smoking only a fraction of a cigarette on each occasion

Krzyzanowski and Lebowitz [17] showed that subjects who continued to smoke during the 11 to 13 years of follow-up ran a two or three times higher risk of developing respiratory symptoms such as dyspnea and attacks of breathlessness compared with lifetime non-smokers

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