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Apart from that, areca nut consumption in large amounts can also cause type IV hypersensitivity reactions and lichenoid-type lesions in oral cavity which at times can induce formation of leukoplakia and sub-mucous fibrosis

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An evidence review conducted in 2018 by Public Health England (now The Office for Health Improvement and Disparities) found that HTP were likely significantly safer than combustible cigarettes, stating: Compared with cigarette smoke, HTP are likely to expose users and bystanders to lower levels of particulate matter and harmful and potentially harmful compounds.[29] New Zealands government has also highlighted that heated products are considered less harmful than smoked products due to the lack of products of combustion, in a paper outlining proposed cuts to excise duty on HTP.[30] They also stated that HTP offer an alternative to vaping for people who smoke and are struggling to quit using vapes

Seventh, because KNHANES produces data representative of Koreans, it is not appropriate to directly extrapolate this studys results to people in other countries