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22 / 26 Compared to nonsmokers, people who smoke or use smokeless tobacco products are more likely to develop oral cancer

Keep in mind that puff count is based on one-second puffs in lab conditions

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Nicotine, the addictive chemical found in tobacco products like cigarettes or vapes, is complex because it acts as both a stimulant and a depressant, depending on the dose, timing, and individual response