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The condition is characterised by: Progressive shortness of breath Persistent dry cough Chest tightness Reduced exercise tolerance In severe cases, respiratory failure The Centers for Disease Control and Prevention (CDC) has extensively documented these cases, noting that the severity of symptoms correlates with the level and duration of diacetyl exposure (5)

87 Also, degradation products of heparan sulfate, ubiquitously present on cell surfaces and extracellular matrix, can activate DCs in vitro

Clementz and J
