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REFERENCES 1.Reynolds American Inc

[20] Randomized controlled trials have provided "high-certainty" evidence that e-cigarettes containing nicotine are more effective than nicotine replacement therapy for discontinuing tobacco smoking, and moderatecertainty evidence that they are more effective than e-cigarettes free of nicotine

Both the number of cigarettes smoked and smoking duration are strongly associated with mortality risk and the number of lifeyears lost

Experiencing high levels of positive emotion on a daily basis was linked to less frequent cannabis use