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Apparently, nicotine has the effect of changing VSMCs from differentiated to dedifferentiated type, that is transformation from the contractile-type to the synthetic-like (proliferative) type

You're also at higher risk if you: Have a condition that affects your lungs like asthma or chronic obstructive pulmonary disease (COPD) Have another serious health condition like heart disease or diabetes Have a weakened immune system, from a condition like AIDS, from getting chemotherapy, or if you had an organ transplant Spend time in a health care facility such as a hospital or long-term care home Have trouble swallowing Use a ventilator Smoke or are exposed to secondhand smoke Misuse alcohol or drugs Spend time in an environment in which you breathe in irritants like dust, fumes, or chemicals Pneumonia Diagnosis Your doctor will start with questions about your symptoms and your medical history, like whether you smoke and whether youve been around sick people at home, school, or work

However, mindless snacking on junk food isnt ideal

Clearly Mario has it down but I assume Mario avoided explaining it due to his poor English