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These unmeasured factors might have influenced the observed associations

That might be because more people are becoming infected, and infections are being detected more frequently

Mendez and Warner were optimistic that smoking prevalence would continue to fall on course, as it had in the early 2000s, but they concluded that major reductions, such as those presented in the Healthy People 2010 target, were unrealistic (Mendez and Warner 2004)

Although some people argue that vapour from e-cigarettes and vaporisers do not contain the same harmful chemicals found in smoke from regular cigarettes, exposure to vapour from e-cigarettes and vaporisers is still harmful to health