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In the 1960s, the externally-fed fire box method of flue-curing was converted to a gas-fueled system, for the most part, which takes far less time to complete, usually about 7-8 days to cure, compared to the air-cured method that takes about 4 to 8 weeks

Because of this interaction with the CYP450 enzymes, the prescription drugs or cannabinoids may become more concentrated in the system, which could reduce the efficacy of the drug or result in increased negative side effects from the medication

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