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Description
In the case of treatment with INS with low systemic bioavailability (1%), such as mometasone furoate and fluticasone propionate, no statistically significant risk of SIH during therapy for at least 3 months was observed

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37 However, pegbelfermin administered weekly for 48 weeks did not achieve a one-stage or greater improvement in the NASH Clinical Research Network fibrosis score without worsening NASH, as assessed via biopsy in the phase 2B FALCON 2 study (NCT03486912)
