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Description
Clinical data shows that most participants in tirzepatide trials regained significant weight within one year of stopping treatment

This reduction limits the secretion of CXCL9, another key chemokine of the CXCL family, and CXCL10, thereby restricting effector T cell entry into tumor lesions and creating a T cell exclusion state that undermines the efficacy of PD-1/PD-L1 inhibitors

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Not only can menopause drastically increase this risk, but the blood vessels lose elasticity as we age, which can accelerate plaque buildup in the arteries
