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Description
Subtle differences with respect to interactions with the ECLsspecifically, the TM 6-ECL3-TM7/TM1have led to biased agonism (i.e., selective agonism of the cAMP signaling pathway)
The sign-in flow should reduce friction, while still preserving essential safeguards

[1] Antacids or alginates may help if reflux contributes to your symptoms

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