semaglutide injection sites weight loss (Ozempic) Side Effects & Management The MedHealth 360 Guide to

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Risk of Thyroid Issues: There have been concerns about a possible increased risk of thyroid cancer with GLP-1 medications, but this risk is still being evaluated

maintaining hydration is important Common side effects (affecting up to 1 in 10 people): Vomiting Constipation Due to slowed gastric emptying Abdominal pain or discomfort Reduced appetite This is partly how the medication aids blood glucose control Indigestion or acid reflux Fatigue or dizziness Hypoglycaemia (low blood sugar) Particularly when used with other diabetes medications such as sulphonylureas or insulin Gallbladder problems Including gallstones When to seek medical advice: Contact your GP or diabetes team promptly if you experience: Severe, persistent abdominal pain particularly if radiating to the back, as this could indicate pancreatitis (rare but serious)

Besides diabetes, GLP - 1RAs have exhibited gut microbiota - modifying effects in other metabolic disorders, especially some bacteria associated with glycolipid metabolism and intestinal inflammation (Liu et al., 2020b