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If a patient is transitioning between serotonergic agents, physicians should observe a safe washout period to prevent overlap

Methodology: The study authors conducted an exhaustive search through Medline and the Cochrane Library for RCTs assessing the maintenance doses of subcutaneous tirzepatide at 5, 10, or 15 mg once-weekly, or subcutaneous semaglutide at 0.5, 1.0, or 2.0 mg once-weekly, spanning a minimum of 12 weeks

Zepbound, Wegovy, and Saxenda are GLP-1 drugs that mimic a hormone that curbs peoples appetites, causing significant weight loss

Approved by the FDA as Mounjaro for type 2 diabetes and Zepbound for chronic weight management, this once-weekly injectable represents a significant advancement in treating metabolic disease