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Thus, taken together, the actions of GLP-1 and/or changes in these central nervous system signals might play an important role in weight loss and reduced fat mass in VSL#3-treated LFD-fed mice

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The results of trial AWARD-7 showed that once-weekly dulaglutide produced clinically meaningful improvements in glycemic control in T2DM patients with moderate-to-severe CKD, with efficacy similar to that of daily insulin glargine as basal therapy in terms of change in HbA1c
