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Current therapeutic approachesincluding supraphysiologic insulin( 19 ), insulin sensitizers( 20 ), leptin( 21, 22 ), and insulin-like growth factor-1 (IGF-1)( 2329 )provide limited metabolic benefit and do not correct the underlying receptor signaling defect

According to the FTCs complaint, New York-based NextMed, along with its founders Robert Epstein and CEO Frank Leonardo III, marketed membership programs starting in early 2022 that offered consumers access to medical providers who could prescribe popular glucagon-like peptide 1 (GLP-1) drugs like Wegovy and Ozempic