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EP Edge Journal Watch Issue 13 (February/March 2026) : When the Signal Outruns the Rulebook (Ultrashort AF, ILR Truth, Metabolic Modulation & Next-Gen PFA Welcome backand thank you for being herefor EP Edge Journal Watch (Issue 13, February 2026) This issue of EP Edge Journal Watch tackles a problem we all recognize in 2026 EP: our signal detection (wearables, patches, ILRs) and our energy delivery (PFA variants) are advancing faster than the clinical rules we use to interpret risk and outcomes

Because the upper limit of the two-sided 95% CI for the estimated differences was below 0 kg, superiority of SEM 0.5 mg or SEM 1 mg versus placebo in change in body weight was demonstrated

Understanding this timeline helps set realistic expectations and supports adherence to treatment alongside essential lifestyle modifications recommended in UK clinical guidance

The ACHIEVE-1 results will be presented at ADA's 85th Scientific Sessions and published in a peer-reviewed journal