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GLP-1RAs and osteoclasts The greater degree of bone degradation observed in mice lacking GLP-1R indicates that GLP-1R signaling suppresses osteoclast differentiation and bone resorption
From a chemical point of view, it is a linear peptide comprising 39 amino acids, augmented by a covalently attached lipid chain, which modifies the molecules physicochemical properties and its interactions with plasma proteins
A meta-analysis of individual patient data
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