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In 2021, it resulted in a mean weight loss of roughly 15% and maintenance through decreased appetite

5 Heatmap depicting relative levels (log fold change) of differentially expressed selected candidate genes associated with MASH and fibrosis in semaglutide-treated DIO-MASH mice (a) and CDA-HFD mice (b)

A protocol designed around smaller, more frequent measurements typically calls for a different concentration than one built around larger, less frequent draws and since concentration is simply peptide mass divided by liquid volume, changing either side of that relationship changes the correct water volume