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Description
In addition to reducing plaque size and necrotic core area in Apoe / Irs2 +/ mice, lixisenatide was found to result in a greater proportion of M2-like anti-inflammatory (STAT3 + Arginase-1 + ) macrophages in aortic plaques, with fewer M1-like, pro-inflammatory (STAT1 + iNOS + ) macrophages [134]
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In addition, the ICV infusion of exendin-4 increases CNS activity, promotes BAT activation and white adipose tissue browning, and increases BAT glucose and triglyceride uptake [27]
However, moving from a shot to a pill isnt just about convecoloradoIt comes withcoloradoffs in effectiveness, cost, and daily hassle
