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Description
45,46 While additional trials in patients with HFpEF are warranted before definitive statements can be made regarding the benefits of various incretin therapies in HFpEF, providers may wish to consider the positive results for semaglutide and tirzepatide when choosing among incretin therapies
The lower initial dose of 2.5 mg aims to minimize gastrointestinal symptoms (e.g nausea, vomiting, constipation) but may not lead to significant weight loss
Higher values can signal early insulin resistance or diabetes and may affect your starting dose and monitoring plan
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