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15,392 In Wistar rats, a diet high in fat was found to lead to a decrease in the ratio of OPG/RANKL, which resulted in increased bone resorption and ultimately a reduction in bone mass

doi: 10.1161/CIRCRESAHA.109.215483 180 MattagajasinghIKimC-SNaqviAYamamoriTHoffmanTAJungS-Bet al

On November 6, 2025, federal officials announced agreements with manufacturers of branded GLP-1 medications that significantly reduce prices under a new direct-to-consumer platform known as TrumpRx

N Engl J Med 2022;387(9):852854
