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It does not have long-term safety data
Several companies, such as Pfizer (PF-07976016), Regor Therapeutics (RGT-075), AstraZeneca (AZD5004), and others, are also evaluating their oral GLP-1 candidates to give competition to Novo and Eli Lilly
In addition, data indicate that DPP-4 inhibitors also impact immune cell recruitment and reduced macrophage infiltration seemed to be mediated directly via GLP-1-dependent signaling in a rat nephritis model (71)
Contact your GP within 2448 hours if you experience headaches that progressively worsen despite simple painkillers, persist beyond 48 weeks of stable dosing, or significantly interfere with daily activities
