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In a pre- and post-natal study in rats administered subcutaneous doses of 0.02, 0.10, or 0.25 mg/kg tirzepatide twice weekly from implantation through lactation, F1 pups from F0 maternal rats given 0.25 mg/kg tirzepatide had statistically significant lower mean body weight when compared to controls from post-natal day 7 through post-natal day 126 for males and post-natal day 56 for females

If you are considering splitting your dose, the article on splitting tirzepatide into twice-weekly injections covers the practicalities and considerations

Trial site investigators obtained consent, recruited participants, collected data and adhered to ethical standards

The study findings indicated the potential of donanemab to slow AD progression, particularly in the early stage [50]