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In the REDEFINE trials both components step up together about once a month so the gut adapts

Talk to your doctor about nausea and other weight loss medication side effects If youre having continuing problems with nausea or constipation or if these side effects are severe and interfering with your ability to work, eat, or live your life normally, talk to your doctor
Manufacturers recommend storing unopened vials or pens at 2C to 8C in a standard refrigerator

Rybesus is typically only administered to adults
