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The highest dose of Wegovy (2.4 mg) does not directly equate to any specific dose of Mounjaro, but many healthcare providers consider initiating Mounjaro at a lower starting dose and titrating up based on patient response and tolerance

This reinforces the need for strong analytical evaluation

Regardless of the mechanism, these impairments in ENS signaling could lead to alterations in the gutbrain axis that regulate energy homeostasis, as GF mice are GLP-1 resistant, demonstrating reduced activation of brainstem neurons
