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fda and glp 1 is moving to restrict mass-marketed compounded GLP-1 products that aren't FDA-approved, warning companies they can't market them as equivalent to approved drugs signaling stronger enforcement to protect patients from unverified The New York Times spotlighted
Description
Key issues include the need for mechanistic validation in human models, optimizing localized delivery to enhance retinal bioavailability, and ensuring long-term safety

Ozempic and Rybelsus are not FDA approved to treat type 2 diabetes
Rapid hepatic metabolism blunts the endocrine action of portally infused GLP-1 in male rats

11% of American adults are on a GLP-1 right now, nearly four times as many as in 2024
