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Tirzepatide can mitigate this rebound if introduced at the right time (typically 36 months post-abstinence), but starting too early risks destabilizing psychiatric recovery

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The dual mechanism also means tirzepatide may produce faster weight loss, which can heighten early gastrointestinal adjustment

A rare occurrence of non-classic congenital adrenal hyperplasia and type 1 diabetes mellitus in a girl with Prader-Willi Syndrome: Case report and review of the literature