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The starting dose is 0.25 milligrams for 4 weeks before increasing the dosage to 0.5 milligrams

Phentermine increases alertness, and if taken too late in the day, sleep becomes difficult or impossible

J Clin Endocrinol Metab (2006) 91(9):340410

These problems may affect a persons quality of life, leading to missed work and increased hospital visits
