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GLP-1 receptor agonists, including semaglutide and tirzepatide, have revolutionized the approach to weight loss

Berberine (BBR) exhibits significant anti-diabetic effects by enhancing insulin sensitivity, promoting glycolysis, and inhibiting gluconeogenesis

This Canadian development could have broader implications across North America, potentially influencing how metabolic health treatments are delivered and priced in the future

This is the first retrospective trial to evaluate the clinical impact of GLP-1 RAs for patients withmoderate PAD
