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[ref] A 2025 study showed that patients with RLS had higher serum IL-13 (inflammatory cytokine) levels and altered natural killer cell levels.[ref] The IL-13 connection is interesting, since IL-13 is elevated in asthma and allergies, tying back to altered histamine levels in the brain

For instance, while GLP-1 agonists are primarily metabolised by the kidneys and have a low potential for significant drug-drug interactions, it is still important to monitor patients closely when combining therapies

Once breastfeeding has fully stopped and milk production has ceased, there is no required waiting period before starting semaglutide or tirzepatide

This is why staying hydrated isnt just about comfortits a critical part of your safety profile