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The anorectic effects of centrally administered OXM were also abolished in Glp-1r -/- knock-out mice and not in Gcgr -/- mice, suggesting that the anorectic effects of OXM are mediated through GLP-1R

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For example, naltrexone-bupropion is not suitable for patients with uncontrolled hypertension [62] and phentermine is contraindicated in patients with a history of cardiovascular disease [63]

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This is what it must feel like for someone who doesn't have to live with obesity, who has normal appetite regulation and is not thinking about food all the time." Dr

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