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10.1111/dom.12291 138 ZhaoL.ChenY.XiaF.AbudukerimuB.ZhangW.GuoY.et al (2018)

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"We are not saying that semaglutide reverses aging or makes people younger," said the study's first author, Michael Corley, associate professor at UC San Diego School of Medicine and the Stein Institute for Research on Aging, in a press statement
The "up to 2 inches" is the maximum waist reduction seen, not the average the typical effect was more modest (around half an inch)
