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However, immune neutralization of GIP or removal of GIP from intestinal extracts does not completely eliminate the insulin-stimulating activity, indicating that there are other substances with insulin-stimulating activity in the intestine (Drucker, 1998)

long-term medication costs because for some, a one-time surgical investment can be more affordable than years of monthly meds

Importantly, efpeglenatides immunogenicity remained relatively low, with few patients developing clinically significant anti-drug antibodies, allowing its safety profile to be viewed as manageable within class expectations