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It also maintained the possibility for MA holders to extend twice the orphan market-exclusivity period by 12 months, based on approval of a new orphan indication

Patients in clinical trials not only lost significant weight around 15% of their body weight but also experienced enhancements in cardiovascular health, blood sugar control, joint comfort, mobility, sleep quality, and overall confidence

Patients should seek immediate medical attention if this occurs

Research indicates that tirzepatide users often require dose escalation strategies different from semaglutide protocols, with some patients reaching therapeutic goals at maintenance doses lower than they would with semaglutide alone