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Co-delivery of multiple drugs Combination therapy has emerged as a strategic modality for treating complex diseases, particularly metabolic disorders, cancer, and neurodegenerative conditions, where monotherapies often fail to address the multifactorial pathophysiology or elicit sustained responses

Experimental studies have demonstrated that antidiabetic agents, particularly GLP-1RAs (such as liraglutide) and SGLT2is (such as canagliflozin), exert significant cardioprotective effects against myocardial ischemia/reperfusion (I/R) injury in the context of diabetes