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The patented active ingredient, Amarasate, is encased in a delayed-release capsule for targeted release, triggering the bitter taste receptors (TAS2R) of enteroendocrine cells predominantly found along the duodenum

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Hartmann P, American Journal of Physiology Gastrointestinal and Liver Physiology (Vol 329, Issue 6, Dec 1, 2025, pp G680G695)
