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Recommended starting dose: Discontinue other basal insulin and/or GLP-1 agonist before initiating Soliqua Patients naive to basal insulin or a GLP-1 agonist, currently on a GLP-1 agonist or less than 30 units of basal insulin daily: starting dose is 15 units once daily Patients currently on 30 to 60 units of basal insulin daily, with or without a GLP-1 agonist: starting dose is 30 units once daily Maintenance: titrate dose up or down by 2 - 4 units every week based on blood sugar goals Missed doses: resume dosing at the next scheduled dose

Cases of pancreatitis can be managed according to standard ED practice and logically, the GLP-1 agent should be stopped

www.fda.gov/Drugs/DrugSafety/ 18

Some lactobacillus strains and beneficial bacteria have shown a significant reduction in visceral fat in studies, or major effects on bloating
