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PMID: 39327688 Br J Pharmacol Role of LRP5/6/GSK-3/-catenin in the differences in exenatide- and insulin-promoted T2D osteogenesis and osteomodulation

It costs three to six times more to make than a vial

They also come with specific instructions around how and when they need to be taken, and they may not fully replace the role of higher-dose injectable treatments for every patient

The ideal candidate profile for favourable safety outcomes looks something like this: generally good baseline health, no history of pancreatitis or thyroid cancer, no active GI conditions, not pregnant or planning to become pregnant, not using multiple glucose-lowering medications simultaneously, and willing to follow a genuine slow-escalation protocol rather than rushing to maximum dose
