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190 In general, cyanopyrrolidines such as saxagliptin are competitive inhibitors rather than noncompetitive inhibitors of DPP-IV enzymatic activity since they form reversible covalent bonds with serine residue 630 located within the enzyme's active site
Understanding GLP-1 and its Importance This drug class mimics the natural body hormones in encouraging insulin secretion and regulating blood sugar levels, besides inducing weight loss

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