glp 1 and pregnancy JCI Insight GLP-1 receptor agonists and preconception
Description
Phase 2 trials showed significant weight loss up to 20% at 52 weeks

This guide explores prescription options, compounded alternatives, and how genetic and biomarker factors may inform provider conversations about suitability

These medications, which include Novo Nordisks semaglutide, sold as Ozempic and Wegovy, and Eli Lillys tirzepatide, sold as Zepbound and Mounjaro, []

Although rare, associations with nonarteritic anterior ischemic optic neuropathy, pancreatitis, medullary thyroid carcinoma, and acute kidney injury (AKI) have been reported, primarily through pharmacovigilance and case-based evidence