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The study also discovered the roles of 1-adrenergic and - and -opioid receptors in this process

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This is partly due to tirzepatide's mechanism of action as a double agonist, permitting it to assert a more significant decrease in hyperglycemia as compared to glucagon-like peptide (GLP-1) agonists on their own [8]

JAMA Psychiatry , 82(1), 94-98
