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For liraglutide, however, the dosing was more consistent over the study period

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When initiating GLP-1based therapy, clinicians should adhere to the principle of do no harm , particularly during the early phases of treatment when gastrointestinal adverse effects are most likely to emerge (3)

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If orforglipron performs as expected, it could greatly reduce the demand for injections, expand access for those hesitant about needles, and introduce more competition in the GLP-1 space, which could eventually lead to lower prices

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2d) whilst no significant change was observed after Ex4 injection (Fig

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