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Future clinical trials should aim to distinguish the direct analgesic effects of GLP-1RAs from their metabolic benefits and explore their broader applications in pain conditions

By inhibiting the action of DPP-4, sitagliptin helps to increase the levels of these helpful hormones, which in turn stimulates insulin production and lowers blood glucose levels

Understanding your pen's lifespan helps you plan refills and treatment continuity

The more meaningful question is not: Do patients regain weight after stopping GLP-1s? It is: How should we transition patients from pharmacologic support to long-term weight maintenance? Obesity is a chronic disease